Multimodal
pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
Mar 10, 2021
Category: Research
01 March 2021
Pooled CRISPR perturbation screens with multimodal RNA and protein single-cell profiling readout (Perturb-CITE-seq) applied to patient-derived melanoma and tumor-infiltrating lymphocyte co-cultures identifies new tumor immune evasion mechanisms.
Chris J. Frangieh, Johannes C. Melms et al.
Nature Genetics, 1-10